The amnion as a window into human pluripotency

In this issue of Cell Stem Cell, a new study by Rostovskaya et al. (2022) uses human stem cells to understand the formation of the amnion, a vital extraembryonic tissue that encircles the fetus during gestation. They provide insight into human amnion formation and reveal differences in developmental competency of naive and primed human pluripotent stem cells. In this issue of Cell Stem Cell, a new study by Rostovskaya et al. (2022) uses human stem cells to understand the formation of the amnion, a vital extraembryonic tissue that encircles the fetus during gestation. They provide insight into human amnion formation and reveal differences in developmental competency of naive and primed human pluripotent stem cells.