Analysis of Factors Associated with Hemorrhagic Transformation in Acute Cerebellar Infarction

Hemorrhagic transformation (HT) is a frequent and severe complication of ischemic stroke. This study aimed to evaluate the factors associated with the occurrence of HT in patients with acute cerebellar infarction. A total of 190 patients, 141 male (74.2%) and 49 female (25.8%) with mean age 61.84 ±...

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Veröffentlicht in:Journal of stroke and cerebrovascular diseases 2022-07, Vol.31 (7), p.106538-106538, Article 106538
Hauptverfasser: Wang, Lanjing, Liu, Lijun, Zhao, Yanhong, Gao, Di, Yang, Yanhong, Chu, Min, Teng, Jijun
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Sprache:eng
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Zusammenfassung:Hemorrhagic transformation (HT) is a frequent and severe complication of ischemic stroke. This study aimed to evaluate the factors associated with the occurrence of HT in patients with acute cerebellar infarction. A total of 190 patients, 141 male (74.2%) and 49 female (25.8%) with mean age 61.84 ± 12.16 years, who were admitted within 72 h of acute cerebellar infarction onset from January 2017 to March 2021 were retrospectively recruited. The multivariate logistic regression analysis was used to evaluate the independent influent factors for HT and receiver-operating characteristic (ROC) curve was applied to calculate the predictive value of those factors for HT in patients with acute cerebellar infarction. 37 out of 190 recruited patients (19.47%) had HT within 14 days after acute cerebellar infarction onset. The incidence rates of HT occurring within 3 days, 3–7 days and 7–14 days were 13.5%, 40.5% and 45.9%, respectively. Results of the multivariable logistic regression analysis indicated that atrial fibrillation (AF) (OR 6.196, 95% CI 1.357-28.302, P = 0.019), infarct diameter (OR 5.813, 95% CI 2.932-11.526, P 
ISSN:1052-3057
1532-8511
DOI:10.1016/j.jstrokecerebrovasdis.2022.106538