Efficacy and safety of AnluoHuaxian pills on chronic hepatitis B with normal or minimally elevated alanine transaminase and early liver fibrosis: A randomized controlled trial

The AnluoHuaxian pill (AHP) is a widely used patented medicine for chronic hepatitis B (CHB) patients with advanced fibrosis or cirrhosis that has been used in China for more than 15 years. However, data are lacking on whether monotherapy with AHP can be effective in CHB patients with alanine aminot...

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Veröffentlicht in:	Journal of ethnopharmacology 2022-07, Vol.293, p.115210-115210, Article 115210
Hauptverfasser:	Xiao, Huan-Ming, Shi, Mei-Jie, Jiang, Jun-Min, Cai, Gao-Shu, Xie, Yu-Bao, Tian, Guang-Jun, Xue, Jing-Dong, Mao, De-Wen, Li, Qin, Yang, Hong-Zhi, Guo, Hui, Lei, Chun-Liang, Lu, Wei, Chen, Liang, Liu, Hua-Bao, Wang, Jing, Gao, Yue-Qiu, Chen, Jie-Zhen, Wu, Shu-Duo, Chen, Hui-Jun, Zhao, Peng-Tao, Zhang, Chao-Zhen, Ou-Yang, Wen-Wei, Wen, Ze-Huai, Chi, Xiao-Ling
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine - therapeutic use Alanine Transaminase China chronic hepatitis B Chronic hepatitis B infection confidence interval Drugs, Chinese Herbal fibrosis Hepatitis B, Chronic - drug therapy hepatoma Histological change, AnluoHuaxian histology Humans liver Liver - pathology liver cirrhosis Liver Cirrhosis - drug therapy Liver Cirrhosis - pathology Liver fibrosis odds ratio Oriental traditional medicine patients placebos randomized clinical trials Randomized controlled trial risk sample size Traditional Chinese medicine
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Beschreibung
Zusammenfassung:	The AnluoHuaxian pill (AHP) is a widely used patented medicine for chronic hepatitis B (CHB) patients with advanced fibrosis or cirrhosis that has been used in China for more than 15 years. However, data are lacking on whether monotherapy with AHP can be effective in CHB patients with alanine aminotransferase (ALT) levels less than 2 times the upper limit of normal (ALT
ISSN:	0378-8741 1872-7573
DOI:	10.1016/j.jep.2022.115210