Facile synthesis of highly tunable monodispersed calcium hydroxide composite particles by using a two-step ion exchange reaction

"Calcium hydroxide [Ca(OH) 2 ]" is a medicament frequently used for antimicrobial purposes in endodontic procedures, or it is used as a toxic-waste adsorbent in industry. Ca(OH) 2 particles produced through conventional methods are size untunable and have a wide size distribution and polyg...

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Veröffentlicht in:RSC advances 2020-04, Vol.1 (23), p.137-1377
Hauptverfasser: Yang, Chih-Hui, Wang, Ya-Chin, Wang, Ta-Chen, Chang, Yi-Ching, Lin, Yun-Chul, Chen, Pei-Fan, Huang, Wei-Jie, Wen, Hsin-Yi, Lin, Yu-Mei, Kuo, Wen-Shuo, Wang, Yi-Ting, Huang, Keng-Shiang
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Sprache:eng
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Zusammenfassung:"Calcium hydroxide [Ca(OH) 2 ]" is a medicament frequently used for antimicrobial purposes in endodontic procedures, or it is used as a toxic-waste adsorbent in industry. Ca(OH) 2 particles produced through conventional methods are size untunable and have a wide size distribution and polygonal shape. In this paper, a novel and facile approach involving template-mediated synthesis and two-step ion exchange is proposed for uniform size Ca(OH) 2 composite particles generation. "Sodium-alginate (Na-alginate)" was used as a precursor, and monodisperse Na-alginate emulsions were formed through needle droplet or droplet microfluidic technology. After the first ion exchange step with the Ca 2+ ions, "calcium-alginate (Ca-alginate)" particles were obtained. The Ca-alginate particles were intermediate reaction products and were designed to be the templates for ensuring the spherical shape and size of products. The OH − ions were used for the second ion exchange step to fabricate Ca(OH) 2 composite particles. The results revealed that the Ca(OH) 2 composite particles were size tunable, had a spherical shape, and were monodisperse (with a relative standard deviation of less than 8%). The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay revealed that the Ca(OH) 2 composite particles were potential biocompatible materials. The synthesized Ca(OH) 2 composite particles were size tunable, had a spherical shape, and were monodisperse.
ISSN:2046-2069
2046-2069
DOI:10.1039/d0ra01275k