Locally advanced pancreatic cancer: a reliable contraindication to resection in the modern era?

The aim of this study is to present radiologically designated LAPC found to be resectable upon surgical exploration and evaluate the outcomes of such resections. Sequential LAPC patients between 2013 and 2019 were staged and underwent resection were included in the analysis of both perioperative and...

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Veröffentlicht in:HPB (Oxford, England) England), 2022-10, Vol.24 (10), p.1789-1795
Hauptverfasser: Fromer, Marc W., Wilson, Khaleel D., Philips, Prejesh, Egger, Michael E., Scoggins, Charles R., McMasters, Kelly M., Martin, Robert C.G.
Format: Artikel
Sprache:eng
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Zusammenfassung:The aim of this study is to present radiologically designated LAPC found to be resectable upon surgical exploration and evaluate the outcomes of such resections. Sequential LAPC patients between 2013 and 2019 were staged and underwent resection were included in the analysis of both perioperative and long-term outcomes. Twenty-eight patients with radiologically-designated LAPC underwent surgical resection after chemotherapy with a median follow-up of 31.7 m,75% underwent pancreaticoduodenectomy. The margin positivity and local recurrence rates were 21.4% and 35.7%, respectively. When compared to the 30 BRPC controls, the LAPC group had a higher rates of an arterial resection (11vs.1; p = 0.002), but the groups were similar with regard to all other preoperative and intraoperative variables (p 
ISSN:1365-182X
1477-2574
DOI:10.1016/j.hpb.2021.09.002