Event‐free survival after radical prostatectomy according to prostate‐specific membrane antigen‐positron emission tomography and European Association of Urology biochemical recurrence risk groups

Objective To assess European Association of Urology (EAU) risk groups for biochemical recurrence (BCR) of prostate cancer relative to prostate‐specific membrane antigen‐positron emission tomography (PSMA‐PET) status and oncological outcomes. Patients and Methods A retrospective analysis of a study that incorporated PSMA‐PET for men with BCR after radical prostatectomy (RP) was undertaken. EAU risk groups were considered relative to clinical variables, PSMA‐PET findings, and deployment of salvage radiotherapy (SRT). The primary oncological outcome was event‐free survival (EFS) and this was analysed relative to clinical and imaging variables. An ‘event’ occurred if prostate‐specific antigen (PSA) level rose >0.2 ng/mL above nadir or additional therapies were introduced. Results A total of 137 patients were included, most of whom had EAU high‐risk disease (76%) and/or low PSA levels (80%