Outcomes of patent ductus arteriosus ligation in very low birth weight premature infants: A retrospective cohort analysis

Patent ductus arteriosus (PDA) can be a significant hemodynamic problem in preterm infants leading to increased morbidity and mortality. PDA ligation is therefore considered an urgent procedure in infants who have failed medical therapy. However, there is controversy regarding optimal timing and decision to operate. This study aimed to evaluate the outcomes and efficacy of PDA ligation in very low birth weight premature infants. We performed a retrospective review of our institution's database and included very low birth weight premature infants (