A Study on the Prevalence of Diabetes Mellitus in Chronic Pancreatitis at a Tertiary Care Hospital

Chronic pancreatitis is characterized by pancreatic inflammatory and fibrotic injury that results in loss of pancreatic structure both exocrine and endocrine functions, often leading to complications like glucose intolerance and Diabetes Mellitus. Diabetes secondary to pancreatic diseases is classified as pancreatic diabetes or type 3c diabetes. Diabetes secondary to chronic pancreatitis differs metabolically and clinically from other types of Diabetes Mellitus. In chronic pancreatitis there is loss of Beta cell mass along with alpha and other cell masses. Pancreatic Diabetes is characterized by impaired Insulin secretion in response to ingestion of meal. Type 3c Diabetes accounts for 5-10% of all cases of diabetes in Western Population. In this Cross Sectional study patients presenting to a tertiary care centre with typical clinical and radiological features of Chronic pancreatitis were investigated for the prevalence of Diabetes Mellitus. CT scan was used as the imaging modality of choice to detect Chronic Pancreatitis. Material: In this Cross Sectional study 60 patients who presented with typical clinical and radiological features of Chronic pancreatitis were investigated for Diabetes Mellitus. CT scan was used as the imaging modality of choice to detect Chronic Pancreatitis. Observation: The prevalence of Diabetes Mellitus in patients of Chronic Pancreatitis in our study was 61.6%. The prevalence of exocrine insufficiency in patients of Chronic pancreatitis in our study was 68.3% Conclusion: Diabetes Mellitus should be specifically sought for while managing the pain of Chronic Pancreatitis patient.