Serum Magnesium Levels and its Association with Glycated Hemoglobin in Type 2 Diabetes Mellitus Patients

Diabetes mellitus is a group of common metabolic disorders that share the phenotype of hyperglycaemia. Like most other chronic disorders, diabetes increases the excretion of minerals and other nutrients. Magnesium is a micronutrient and the second most abundant intracellular cation whose concentration remains remarkably constant in healthy subjects. It is known to activate enzymes and act as important cofactor in various biochemical reactions. Also, Magnesium is required for insulin secretion and for proper insulin functioning via tyrosine kinase activity at the receptor level. Therefore, through this study an attempt has been made to evaluate the association between serum magnesium levels and the glycaemic status of these patients as measured in the form of HbA1c. The study is conducted in the General Medicine ward of a tertiary care hospital in Assam for 4 months, which included 140 patients of Type 2 Diabetes Mellitus. Patients were subjected to history and examination, investigations and analysed using simple statistical methods. In the present study, HbA1C of >7% was taken as poor glycaemic control and the mean magnesium level in this group was 1.46±0.50 mg/dl and in the group with