Biological characterization and genomic analysis of Acinetobacter baumannii phage BUCT628

Acinetobacter baumannii is an opportunistic pathogen that is resistant to the most commonly used antibiotics. In this study, the Acinetobacter phage BUCT628 was isolated from hospital wastewater. BLASTn analysis showed that the genome sequence of BUCT628 shared 89.76% identity with 66% query coverag...

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Veröffentlicht in:	Archives of virology 2022-06, Vol.167 (6), p.1471-1474
Hauptverfasser:	Zhu, Yinuo, Han, Ke, Chen, Long, Luo, Shizhong, Fan, Huahao, Tong, Yigang
Format:	Artikel
Sprache:	eng
Schlagworte:	Acinetobacter Acinetobacter baumannii Annotated Sequence Record Antibiotics Biomedical and Life Sciences Biomedicine Genomes Genomic analysis Infectious Diseases Medical Microbiology Medical wastes Nucleotide sequence Open reading frames Opportunist infection Phages Virology Wastewater
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Beschreibung
Zusammenfassung:	Acinetobacter baumannii is an opportunistic pathogen that is resistant to the most commonly used antibiotics. In this study, the Acinetobacter phage BUCT628 was isolated from hospital wastewater. BLASTn analysis showed that the genome sequence of BUCT628 shared 89.76% identity with 66% query coverage with that of Acinetobacter phage Bphi-R2919. Genome sequencing showed that the BUCT628 genome is a 44,935-bp linear dsDNA molecule with 37.5% G+C content and 86 open reading frames (ORFs), and no tRNAs were identified.
ISSN:	0304-8608 1432-8798
DOI:	10.1007/s00705-022-05425-7