Age at first syncope: a consideration for assessing probable cause?

Graphical Abstract Graphical Abstract Illustration depicting how patient selection may bias findings. It may reasonably be assumed that only a portion of all syncope/collapse patients are evaluated and from that subset of all patients many were excluded from the study (Left) for various reasons. These excluded patients (e.g., classic VVS or OH cases) would impact the subset of the overall patient population evaluated for first syncope (Right) and inevitably the conclusion that age at first syncope may be a helpful diagnostic tool (see subsection entitled Limitations in this Editorial).