Production of pilot batches 223Ra and 227Th of medical purpose

The pilot batches of 227ThCl4 and 223RaCl2 were separated from 227Ас. 227Th was separated by anion exchange chromatography on the sorbent BioRad AG-1x8 100–200 mesh from 8 М HNO3. After 227Th storage accumulated 223Ra was separated from 227Th using two chromatography columns: on sorbent BioRad AG-1x8 100–200 mesh from 8 М HNO3 followed by eluate evaporation, by dissolving of dry residue in 0.02 М EDTA with рН 4.5 and sorption on cation exchanger BioRad AG-50x8 200–400 mesh. The samples obtained were analyzed by gamma-, alpha- and atomic emission spectrometry methods. Long-living 227Ас content in Ra and Th was determined by a preliminary chemical separation. •Three pilot batches of 227ThCl4 with volumetric activity 7.0∙106 Bq/ml, 6.1∙105 Bq/ml and 5.7∙107 Bq/ml were produced.•Four pilot batches 223RaCl2 with volumetric activity from 1.2∙107 to 3.7∙107 Bq/ml were separated.•Minimum reached limits of 227Ас detection were 8.6∙10−5% and 2.6∙10−6% from activity of 227Th and 223Ra respectively.