Comparisons of size of foveal avascular zone area among children with posterior microphthalmos, high hyperopia, and normal eyes

Purpose To determine the area of the surface foveal avascular zone (FAZ) in children with posterior microphthalmos (PM), high hyperopia, and normal eyes using optical coherence tomography (OCT) and OCT angiography (OCTA). Methods Thirty-six children were studied including 6 cases 12 eyes of PM (mean age 9.5 ± 5.2 years), 15 cases 30 eyes of high hyperopia (6.9 ± 1.5 years), and 15 cases 30 eyes of healthy individuals (8.7 ± 1.7 years). The B- and C-scan images in all children were recorded by OCT and OCTA with a scanning area of 3.0 × 3.0 mm centered on the fovea. All images were corrected for axial length differences, and the area of the FAZ surface and central macular thickness (CMT) was measured manually and compared. Results The area of FAZ in the PM group was 0.007 ± 0.003 mm 2 , which was significantly smaller than that in the high hyperopia eyes at 0.286 ± 0.108 mm 2 and healthy eyes at 0.318 ± 0.129 mm 2 (both P