PI3K/AKT/Nrf2 signalling pathway is involved in the ameliorative effects of xanthohumol on amyloid β-induced oxidative damage and bone loss

Xanthohumol (XAN), a natural isoflavone from Humulus lupulus L., possesses biological activities on relieving oxidative stress and osteoporosis (OP). This study aimed to evaluate the antioxidative and osteoprotective effect of XAN on Aβ-injured osteoblasts, and explore its underlying mechanism. Oste...

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Veröffentlicht in:	Journal of pharmacy and pharmacology 2022-07, Vol.74 (7), p.1017-1026
Hauptverfasser:	Xia, Tianshuang, Liu, Xiaoyan, Wang, Nani, Jiang, Yiping, Bai, Huanhuan, Xu, Weifan, Feng, Kunmiao, Han, Ting, Xin, Hailiang
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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