Detection of hemoglobin Kinshasa by a capillary electrophoresis method

•Hemoglobin Kinshasa is a rare mutation affecting the stop codon of the α2 gene (c.428A > T)•Hemoglobin Kinshasa can be detected by capillary electrophoresis of hemoglobin.•HbA1 and HbA2 hemoglobin variant are important to detect because they can lead to hemoglobin H disease if associated with an...

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Veröffentlicht in:	Clinica chimica acta 2022-06, Vol.531, p.81-83
Hauptverfasser:	Deltombe, Matthieu, Benamour, Meryem, Derclaye, Isabelle, Maisin, Diane
Format:	Artikel
Sprache:	eng
Schlagworte:	Capillary electrophoresis Hemoglobin Hemoglobinopathy Kinshasa α-Thalassemia
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description	•Hemoglobin Kinshasa is a rare mutation affecting the stop codon of the α2 gene (c.428A > T)•Hemoglobin Kinshasa can be detected by capillary electrophoresis of hemoglobin.•HbA1 and HbA2 hemoglobin variant are important to detect because they can lead to hemoglobin H disease if associated with an α0-thalassemia carrier.
doi_str_mv	10.1016/j.cca.2022.03.020
format	Article
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subjects	Capillary electrophoresis Hemoglobin Hemoglobinopathy Kinshasa α-Thalassemia
title	Detection of hemoglobin Kinshasa by a capillary electrophoresis method
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