Comparison of the Newborn Infant Parasympathetic Evaluation (NIPE™) index to changes in heart rate to detect intraoperative nociceptive stimuli in healthy and critically ill children below 2 years: An observational study

Background The validity of current tools for intraoperative objective assessment of nociception/antinociception balance during anesthesia in young and very young surgery children is unknown. Aim Primary aim of the study was to test the hypothesis that the Newborn Infant Parasympathetic Evaluation (N...

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Veröffentlicht in:Pediatric anesthesia 2022-07, Vol.32 (7), p.815-824
Hauptverfasser: Neumann, Claudia, Babasiz, Tamara, Straßberger‐Nerschbach, Nadine, Schindler, Ehrenfried, Reuter, Christian, Weinhold, Leonie, Wittmann, Maria, Hilbert, Tobias, Klaschik, Sven
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Sprache:eng
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Zusammenfassung:Background The validity of current tools for intraoperative objective assessment of nociception/antinociception balance during anesthesia in young and very young surgery children is unknown. Aim Primary aim of the study was to test the hypothesis that the Newborn Infant Parasympathetic Evaluation (NIPE) index performs better in indicating nociception in anesthetized children below 2 years than changes in heart rate. Secondary aims were to evaluate associations between intraoperative changes in NIPE index values and postoperative pain and emergence delirium. Methods Fifty‐one children aged
ISSN:1155-5645
1460-9592
DOI:10.1111/pan.14446