On ‘Deuterium exchange of poly-dl-alanine in aqueous solution’ by Arieh Berger and K. Linderstrøm-Lang

On ‘Deuterium exchange of poly-dl-alanine in aqueous solution’ by Arieh Berger and K. Linderstrøm-Lang

This commentary highlights the landmark manuscript published in 1957 by Arieh Berger and K. Linderstrøm-Lang that describes the measurement and analysis of hydrogen exchange rates. This highly referenced manuscript is recognized because the impact hydrogen exchange has had on characterizing the stru...

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Veröffentlicht in:Archives of biochemistry and biophysics 2022-09, Vol.726, p.109185-109185, Article 109185
1. Verfasser: Hinck, Andrew P.
Format: Artikel
Sprache:eng
Schlagworte:
HDX-MS
Hydrogen exchange
NMR
Protein dynamics
Protein stability
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Beschreibung
Zusammenfassung:This commentary highlights the landmark manuscript published in 1957 by Arieh Berger and K. Linderstrøm-Lang that describes the measurement and analysis of hydrogen exchange rates. This highly referenced manuscript is recognized because the impact hydrogen exchange has had on characterizing the structure and dynamics of natively folded proteins and folding intermediates.
ISSN:0003-9861
1096-0384
DOI:10.1016/j.abb.2022.109185