On 'Spin trapping of superoxide and hydroxyl radical: Practical aspects' by Eli Finkelstein, Gerald M. Rosen and Elmer J. Rauckman

This commentary describes a highly cited paper by Eli Finkelstein, Gerald M. Rosen, and Elmer J. Raukman that appeared in Archives of Biochemistry and Biophysics published in 1980. They reviewed many reports being regularly appearing in the literature describing spin trapping and hydroxyl radicals from various sources and contributed to the development and progress that has been made in oxidative stress research. •Direct detection and identification of short-lived free radical.•Most useful spin trap for the study of oxygen-centered free radical.•Spin trapping of superoxide and hydroxyl radical during oxidative stress.