Mitral valve edge‐to‐edge repair versus indirect mitral valve annuloplasty in atrial functional mitral regurgitation

Objectives We aimed to compare indirect mitral annuloplasty using the Carillon Mitral Contour System and edge‐to‐edge repair via MitraClip in atrial functional mitral regurgitation (aFMR). Background In patients with left ventricular dilation, both edge‐to‐edge repair and indirect mitral annuloplasty are effective in reducing mitral regurgitation, while no clinical trial has compared both interventional methods in aFMR. Methods In a retrospective single‐center analysis, 41 patients with aFMR underwent either edge‐to‐edge mitral valve repair (MitraClip group, n = 20) or indirect annuloplasty (Carillon group, n = 21). Results Both treatment groups showed high procedural success (100%) and low complication rates. Both treatment groups showed a comparable reduction of New York Heart Association (NYHA) classification postimplantation, after 3‐ and 12‐months follow‐up. Quantitative reduction in echocardiographic FMR parameters was significantly pronounced in the MitraClip group (reduction in vena contracta MitraClip vs. Carillon: postimplantation −74.6 ± 25.8 vs. −29.1 ± 17.8%, 3‐months follow‐up −65.8 ± 31.2 vs. −33.9 ± 17.5%, 12‐months follow‐up −50.8 ± 27.9 vs. −23.9 ± 17.0%, p