Rapid electrochemical dual-target biosensor composed of an Aptamer/MXene hybrid on Au microgap electrodes for cytokines detection

Rapid detection methods for cytokine storm markers, such as tumor necrosis factor α (TNF-α) and interferon gamma (IFN-γ), are required. Herein, we describe the fabrication of a rapid electrochemical dual-target biosensor composed of aptamer/MXene (Ti3C2) nanosheet on an Au microgap electrode. Altern...

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Veröffentlicht in:	Biosensors & bioelectronics 2022-07, Vol.207, p.114159-114159, Article 114159
Hauptverfasser:	Noh, Seungwoo, Lee, Hoseok, Kim, Jinmyeong, Jang, Hongje, An, Jeongyun, Park, Chulwhan, Lee, Min-Ho, Lee, Taek
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternating current electrothermal flow Aptamer Aptamers, Nucleotide - chemistry Biosensing Techniques - methods Cytokine storm detection Cytokines Electrochemical Techniques - methods Electrodes Gold - chemistry Humans Interferon-gamma Limit of Detection Mxene Oligonucleotides Rapid electrochemical biosensor Tumor Necrosis Factor-alpha
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Zusammenfassung:	Rapid detection methods for cytokine storm markers, such as tumor necrosis factor α (TNF-α) and interferon gamma (IFN-γ), are required. Herein, we describe the fabrication of a rapid electrochemical dual-target biosensor composed of aptamer/MXene (Ti3C2) nanosheet on an Au microgap electrode. Alternating current electrothermal flow (ACEF) significantly reduced the detection time (
ISSN:	0956-5663 1873-4235
DOI:	10.1016/j.bios.2022.114159