Energy metabolism as the target of 3-phenyllactic acid against Rhizopus oryzae

3-phenyllactic acid (PLA) has broad anti-fungal activity, however, target sites of PLA on fungal cells and its anti-fungal mechanism of action have been poorly studied. In this study, we explored the inhibition mechanism of Rhizopus oryzae (R. oryzae) on rotten lily bulbs by PLA. The minimum inhibit...

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Veröffentlicht in:	International journal of food microbiology 2022-05, Vol.369, p.109606-109606, Article 109606
Hauptverfasser:	Fan, Wenguang, Li, Baoyu, Du, Nana, Hui, Tian, Cao, Yingying, Li, Xin, Ren, Haiwei
Format:	Artikel
Sprache:	eng
Schlagworte:	3-phenyllactic acid Acids Aconitic acid Adenosine diphosphate Adenylate kinase Anti-fungal mechanism Apoptosis ATP Cell membranes Citric acid Cytochrome Cytochrome-c oxidase Cytochromes Dehydrogenase Dehydrogenases Electron microscopy Energy Metabolism Enzymatic activity Enzyme activity Fungi Fungicides Gene expression Glycolysis Hexokinase Isocitric acid Ketoglutaric acid Kinases Lactates - metabolism Malic acid Metabolism Metabolites Metabolomics Microscopy Minimum inhibitory concentration Mitochondria Nicotinamide adenine dinucleotide Organelles Oxidative phosphorylation Oxoglutarate dehydrogenase (lipoamide) Phosphorylation Rhizopus - metabolism Rhizopus oryzae Scanning electron microscopy Transmission electron microscopy Tricarboxylic acid cycle Ultrastructure
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