Antibody–Drug Conjugates for Immunology

The application of antibody–drug conjugates (ADCs) to fields outside of oncology is increasing but is still relatively uncommon. A recent publication describes the conjugation of glucocorticoid receptor modulators to antibodies as a means of improving the separation between desired anti-inflammatory...

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Veröffentlicht in:Journal of medicinal chemistry 2022-03, Vol.65 (6), p.4496-4499
1. Verfasser: Dragovich, Peter S
Format: Artikel
Sprache:eng
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Zusammenfassung:The application of antibody–drug conjugates (ADCs) to fields outside of oncology is increasing but is still relatively uncommon. A recent publication describes the conjugation of glucocorticoid receptor modulators to antibodies as a means of improving the separation between desired anti-inflammatory activity and unwanted systemic side effects.
ISSN:0022-2623
1520-4804
DOI:10.1021/acs.jmedchem.2c00339