Factors associated with inability to return to intended oncologic treatment in pancreatic cancer

Return to Intended Oncologic Treatment (RIOT) has been proposed as a quality metric in the care of cancer patients. We sought to define factors associated with inability to RIOT in Pancreatic Ductal Adenocarcinoma (PDAC) patients. The NCDB was queried for patients who underwent pancreaticoduodenecto...

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Veröffentlicht in:	The American journal of surgery 2022-07, Vol.224 (1), p.635-640
Hauptverfasser:	Mickel, T. Alston, Kutlu, Onur C., Silberfein, Eric J., Hsu, Cary, Chai, Christy Y., Fisher, William E., Van Buren, George, Camp, E. Ramsay
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Age Cancer Cancer therapies Carcinoma Carcinoma, Pancreatic Ductal - surgery Chemotherapy Demographic factors Failure analysis Hospitals Humans Male Mortality Neoadjuvant therapy Pancreatectomy Pancreatic cancer Pancreatic ductal Pancreatic Neoplasms Pancreatic Neoplasms - surgery Pancreaticoduodenectomy Patients Regression analysis Regression models Retrospective Studies Surgery Survival Survival analysis
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Zusammenfassung:	Return to Intended Oncologic Treatment (RIOT) has been proposed as a quality metric in the care of cancer patients. We sought to define factors associated with inability to RIOT in Pancreatic Ductal Adenocarcinoma (PDAC) patients. The NCDB was queried for patients who underwent pancreaticoduodenectomy for pathologic stage IB, IIA, or IIB PDAC from 2010 to 2016. Multivariable binary logistic regression models identified factors associated with failure to RIOT, and Kaplan-Meier survival analysis and Cox multivariable regression models demonstrated the impact of failure to RIOT on survival. Increasing age (p
ISSN:	0002-9610 1879-1883
DOI:	10.1016/j.amjsurg.2022.02.058