Influence of chlorhexidine digluconate on biocompatibility of cements: Morphological and immunohistochemistry analysis

Influence of chlorhexidine digluconate on biocompatibility of cements: Morphological and immunohistochemistry analysis

In this study, the in vivo biocompatibility was evaluated by using conventional ionomer cements modified with Chlorhexidine (CHX) in different time intervals. In total, 105 male Wistar rats were randomized into seven groups: control, groups M, M10, M18 and groups RL, RL10, RL18 (M‐Meron and RL‐RivaL...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Microscopy research and technique 2022-07, Vol.85 (7), p.2438-2445
Hauptverfasser: Morais Sampaio, Gêisa Aiane, Meneses, Izaura Helena Chaves, Vieira, Rayssa Amaral, Pithon, Matheus Melo, Alves, Polliana Muniz, Lacerda‐Santos, Rogério
Format: Artikel
Sprache:eng
Schlagworte:
Antibacterial activity
Antiinfectives and antibacterials
Biocompatibility
Cements
Chlorhexidine
Collagen
Giant cells
glass ionomer cements
histology
Immunohistochemistry
In vivo methods and tests
Inflammation
Ionomers
Macrophages
microscope
Tissues
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:In this study, the in vivo biocompatibility was evaluated by using conventional ionomer cements modified with Chlorhexidine (CHX) in different time intervals. In total, 105 male Wistar rats were randomized into seven groups: control, groups M, M10, M18 and groups RL, RL10, RL18 (M‐Meron and RL‐RivaLuting, and added CHX‐10% and CHX‐18%, respectively). Histological analyses of inflammatory infiltrate and collagen fibers, and immunohistochemistry of CD68+ for macrophages (MOs) and multinucleated giant cells (MGCs) were performed. Data were analyzed using the Kruskal–Wallis and Dunn (p 
ISSN:1059-910X
1097-0029
DOI:10.1002/jemt.24099