Experimental models of undifferentiated pleomorphic sarcoma and malignant peripheral nerve sheath tumor

Undifferentiated pleomorphic sarcoma (UPS) and malignant peripheral nerve sheath tumor (MPNST) are aggressive soft tissue sarcomas that do not respond well to current treatment modalities. The limited availability of UPS and MPNST cell lines makes it challenging to identify potential therapeutic tar...

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Veröffentlicht in:	Laboratory investigation 2022-06, Vol.102 (6), p.658-666
Hauptverfasser:	Bhalla, Angela D., Landers, Sharon M., Singh, Anand K., Landry, Jace P., Yeagley, Michelle G., Myerson, Gabryella S. B., Delgado-Baez, Cristian B., Dunnand, Stephanie, Nguyen, Theresa, Ma, Xiaoyan, Bolshakov, Svetlana, Menegaz, Brian A., Lamhamedi-Cherradi, Salah-Eddine, Mao, Xizeng, Song, Xingzhi, Lazar, Alexander J., McCutcheon, Ian E., Slopis, John M., Ludwig, Joseph A., Lev, Dina C., Rai, Kunal, Torres, Keila E.
Format:	Artikel
Sprache:	eng
Schlagworte:	13/106 13/51 45/23 631/67/1798 631/67/70 Animals Cell culture Genes Humans Implants In vivo methods and tests Injection Laboratories Laboratory Medicine Medicine Medicine & Public Health Mice Models, Theoretical Mutation Neoplasia Neoplasms Neurofibrosarcoma - genetics p53 Protein Pathology Peripheral nerves Radiation Retinoblastoma Sarcoma Sarcoma - genetics Sarcoma - pathology Sequence analysis Sheaths Soft Tissue Neoplasms - genetics Soft tissues technical-report Therapeutic targets Tissues Tumor cell lines Tumorigenesis Tumors Xenografts Xenotransplantation
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