Role of multicomponent non-pharmacological nursing interventions on delirium prevention: A randomized controlled study

•Multi-Non-PharmaNIs are evidence-based practices to prevent delirium.•Implementation of orientation strategies in nursing care, ensuring family participation in these strategies, and improving sleep quality have been shown to improve delirium rates in ICUs.•This study confirmed the beneficial effects of Multi-Non-PharmaNIs in reducing the development of delirium in adult patients in the ICU.•In ICU, nurses should apply orientation strategies to patients to reduce delirium, involve families in these strategies, read newspapers and apply eye patches at night to improve sleep quality. Multicomponent-Non-PharmacologicalNursingInterventions (Multi-Non-PharmaNIs) are evidence-based recommendations for the prevention of delirium. Purpose of this randomized controlled trial was to compare the effects of Multi-Non-PharmaNIs on delirium. The Multi-Non-PharmaNIs included orientation strategies (playing audio recordings of a non-family/family member), reading a daily newspaper, andwearing an eye patch at night. The absence/presence of delirium was assessed two times a day for three consecutive days. The patients in Group1 were made to listen to the orientation messages recorded in a non-family member's voice (10 min), was read newspaper, and wore an eye patch at night. Group2 received the same interventions as Group1, only the orientation messages were recorded in a family member's voice. The control group received standard nursing-care. There was a significant difference between 3 groups. When Group1 and Group2 were compared with the control group, it was found that there was a significant difference between Group2 and control group (p