Mimicking Native Liver Lobule Microarchitecture In Vitro with Parenchymal and Non-parenchymal Cells Using 3D Bioprinting for Drug Toxicity and Drug Screening Applications

Bioengineering an in vitro liver model recapitulating the native liver microarchitecture consisting of parenchymal and non-parenchymal cells is crucial in achieving cellular crosstalk and hepatic metabolic functions for accurate hepatotoxicity prediction. Bioprinting holds the promise of engineering...

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Veröffentlicht in:	ACS applied materials & interfaces 2022-03, Vol.14 (8), p.10167-10186
Hauptverfasser:	Janani, G, Priya, Smriti, Dey, Souradeep, Mandal, Biman B
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and Medical Applications of Materials and Interfaces Bioprinting - methods Drug Evaluation, Preclinical Drug-Related Side Effects and Adverse Reactions Endothelial Cells Humans Liver Printing, Three-Dimensional Tissue Engineering - methods Tissue Scaffolds
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