Lance-Adams syndrome: An unusual complication of snakebite envenomation

Neuroparalytic snakebite envenomation is common in tropics and sub-tropics. The clinical history is sometimes unclear and misleading, leading to delay in diagnosis and initiation of life-saving treatments. It often gets so delayed that the patient may end up in neuromuscular respiratory failure. If...

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Veröffentlicht in:Toxicon (Oxford) 2022-04, Vol.209, p.50-55
Hauptverfasser: Ghosh, Ritwik, Maity, Arpan, Biswas, Uttam, Das, Shambaditya, Benito-León, Julián
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Sprache:eng
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Zusammenfassung:Neuroparalytic snakebite envenomation is common in tropics and sub-tropics. The clinical history is sometimes unclear and misleading, leading to delay in diagnosis and initiation of life-saving treatments. It often gets so delayed that the patient may end up in neuromuscular respiratory failure. If sustained hypoxia occurs, a permanent neurological squeal may be the endpoint. We report a novel case of a 21-year-old previously healthy young Indian man who had a rapidly progressive neuroparalytic respiratory failure following a cobra bite for which he required mechanical ventilation for four days. After weaning successfully from the ventilator, he developed Lance-Adams syndrome, which persisted for over a month and eventually responded well to medical treatment. [Display omitted] •Snakebite envenomation is an acute life-endangering neglected tropical and subtropical disease.•Lance-Adams syndrome (LAS) is caused by anoxia of central nervous system.•Clinicians should also be alert about LAS following a neuroparalytic snakebite.
ISSN:0041-0101
1879-3150
DOI:10.1016/j.toxicon.2022.02.008