Minipuberty in born small for gestational age infants: A case control prospective pilot study

Purpose To evaluate minipuberty (MP) in small for gestational age (SGA) infants, both preterm and full-term, during the first year of life. Methods 33 SGA healthy newborns (group A), 21 of which full-term (subgroup A1) and 12 preterm (A2) were enrolled. Control group (B) consisted of 27 AGA, 17 full...

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Veröffentlicht in:Endocrine 2022-05, Vol.76 (2), p.465-473
Hauptverfasser: Pepe, Giorgia, Calafiore, Mariarosa, Velletri, Maria Rosa, Corica, Domenico, Valenzise, Mariella, Mondello, Isabella, Alibrandi, Angela, Wasniewska, Malgorzata, Aversa, Tommaso
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Sprache:eng
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Zusammenfassung:Purpose To evaluate minipuberty (MP) in small for gestational age (SGA) infants, both preterm and full-term, during the first year of life. Methods 33 SGA healthy newborns (group A), 21 of which full-term (subgroup A1) and 12 preterm (A2) were enrolled. Control group (B) consisted of 27 AGA, 17 full-term (subgroup B1) and 10 preterm (B2) infants. Growth parameters, FSH, LH, and Estradiol (E2) or Testosterone (T) serum levels were monitored at 3, 6, and 12 months. Results The gonadotropin surge reached greater increase of LH in males at 3 months and FSH in females at 3, 6 and 12 months ( p  
ISSN:1559-0100
1355-008X
1559-0100
DOI:10.1007/s12020-022-03003-0