Effectiveness of BNT162b2 and mRNA-1273 Second Doses and Boosters for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and SARS-CoV-2-Related Hospitalizations: A Statewide Report From the Minnesota Electronic Health Record Consortium

Using vaccine data combined with electronic health records, we report that mRNA boosters provide greater protection than a 2-dose regimen against SARS-CoV-2 infection and related hospitalizations. The benefit of a booster was more evident in the elderly and those with comorbidities.

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Veröffentlicht in:Clinical infectious diseases 2022-09, Vol.75 (5), p.890-892
Hauptverfasser: Drawz, Paul E, DeSilva, Malini, Bodurtha, Peter, Vazquez Benitez, Gabriela, Murray, Anne, Chamberlain, Alanna M, Dudley, R Adams, Waring, Stephen, Kharbanda, Anupam B, Murphy, Daniel, Muscoplat, Miriam Halstead, Melendez, Victor, Margolis, Karen L, McFarling, Lynn, Lupu, Roxana, Winkelman, Tyler N A, Johnson, Steven G
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Sprache:eng
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Zusammenfassung:Using vaccine data combined with electronic health records, we report that mRNA boosters provide greater protection than a 2-dose regimen against SARS-CoV-2 infection and related hospitalizations. The benefit of a booster was more evident in the elderly and those with comorbidities.
ISSN:1058-4838
1537-6591
DOI:10.1093/cid/ciac110