Fever of Unknown Origin

FUO despite a high-quality workup after a reasonable amount of time has elapsed to rule out self-limited fevers remains a challenge. The clinician must pay close attention to the patient history, aided by the development of molecular diagnostic tests, to distinguish infections from other causes.

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Bibliographische Detailangaben
Veröffentlicht in:	The New England journal of medicine 2022-02, Vol.386 (5), p.463-477
Hauptverfasser:	Haidar, Ghady, Singh, Nina
Format:	Artikel
Sprache:	eng
Schlagworte:	19th century Algorithms Animals Antibiotics Bacterial Infections Clinical Medicine Clinical Medicine General Cross Infection - complications Cross Infection - diagnosis Cytokines Cytomegalovirus Diagnosis, Differential Diagnostics Drug-Related Side Effects and Adverse Reactions Endocarditis Epstein-Barr virus Fever Fever of Unknown Origin - etiology Fungal Infections Global Health Hematologic Neoplasms - complications Hematologic Neoplasms - diagnosis Humans Immunocompromised Host Infections Infections - complications Infections - diagnosis Infectious Disease Infectious Disease General Medical diagnosis Parasitic Infections Patients Surgical Procedures, Operative - adverse effects Thermogenesis Tuberculosis Viral Infections Zoonoses - complications Zoonoses - diagnosis
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Beschreibung
Zusammenfassung:	FUO despite a high-quality workup after a reasonable amount of time has elapsed to rule out self-limited fevers remains a challenge. The clinician must pay close attention to the patient history, aided by the development of molecular diagnostic tests, to distinguish infections from other causes.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMra2111003