Role of Endoplasmic Reticulum Stress in Nano-Selenium Alleviating Prehierarchical Follicular Atresia Induced by Mercury in Laying Hens

Role of Endoplasmic Reticulum Stress in Nano-Selenium Alleviating Prehierarchical Follicular Atresia Induced by Mercury in Laying Hens

This study investigated that the effect of nano-selenium (nano-Se) addition preventing prehierarchical follicular atresia induced by mercury (Hg) exposure in laying hens. Furthermore, endoplasmic reticulum (ER) stress pathway was explored to reveal the protective mechanism of nano-Se in vitro. The r...

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Veröffentlicht in:Biological trace element research 2022-12, Vol.200 (12), p.5205-5217
Hauptverfasser: Ma, Yan, Shi, Yizhen, Wang, Yuqin, Wu, Qiujue, Cheng, Binyao, Li, Yumeng, Wang, Zhuosi, Chai, Xiaoying, Ren, Ao, Li, Gan
Format: Artikel
Sprache:eng
Schlagworte:
17β-Estradiol
Bcl-2 protein
Biochemistry
Biomedical and Life Sciences
Biotechnology
Caspase-3
Caspase-9
Cell viability
Endoplasmic reticulum
Estrogen receptors
Exposure
Follicle-stimulating hormone
Follicles
Gene expression
Granulosa cells
Hormones
Life Sciences
Luteinizing hormone
MAP kinase
Mercury
Nutrition
Oncology
Poultry
Progesterone
Selenium
Sex hormones
TRAF2 protein
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Zusammenfassung:This study investigated that the effect of nano-selenium (nano-Se) addition preventing prehierarchical follicular atresia induced by mercury (Hg) exposure in laying hens. Furthermore, endoplasmic reticulum (ER) stress pathway was explored to reveal the protective mechanism of nano-Se in vitro. The results revealed that Hg could significantly reduce laying performance ( P  
ISSN:0163-4984
1559-0720
DOI:10.1007/s12011-021-03084-4