Multisite Pseudomonas aeruginosa Infections Detected by Metagenomic Next-Generation Sequencing in a Child with Aplastic Anemia: A Case Report

Multisite Pseudomonas aeruginosa Infections Detected by Metagenomic Next-Generation Sequencing in a Child with Aplastic Anemia: A Case Report

Abstract Microbial cultivation is the current gold standard for the clinical diagnosis of bacterial infections. However, this method sometimes produces false negative results. We present a case study of multisite Pseudomonas aeruginosa infections detected by metagenomic next-generation sequencing in...

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Veröffentlicht in:Laboratory medicine 2022-09, Vol.53 (5), p.e123-e125
Hauptverfasser: Lai, Shu-yu, Liu, Fang, Chang, Li, Che, Guang-lu, Yang, Qiu-xia, Jiang, Yong-mei, Teng, Jie
Format: Artikel
Sprache:eng
Schlagworte:
Anemia
Antibiotics
Aplastic anemia
Bacterial infections
Blood
Case reports
Cellulitis
Disease
Drug resistance
Fever
Health aspects
Hospitals
Imipenem
Infection
Infections
Lavage
Medical research
Medicine, Experimental
Pathogens
Patients
Pediatrics
Pseudomonas aeruginosa
Pseudomonas aeruginosa infections
Tazobactam
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Zusammenfassung:Abstract Microbial cultivation is the current gold standard for the clinical diagnosis of bacterial infections. However, this method sometimes produces false negative results. We present a case study of multisite Pseudomonas aeruginosa infections detected by metagenomic next-generation sequencing in a child with aplastic anemia, highlighting the rapid and accurate advantages of this technique.
ISSN:0007-5027
1943-7730
DOI:10.1093/labmed/lmab123