Hemostatic status in women with breast cancer and cardiotoxicity associated to doxorubicin-based chemotherapy – A one-year follow-up study
•Patients with breast cancer and doxorubicin-based chemotherapy present a hypercoagulable state.•Thrombin generation showed changes in patients using doxorubicin according to cardiotoxicity.•Thrombin generation parameters may be useful in monitoring hemostasis in these patients.
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Veröffentlicht in: | Thrombosis research 2022-03, Vol.211, p.56-59 |
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container_title | Thrombosis research |
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creator | Pestana, Rodrigo M.C. Duarte, Rita C.F. Alves, Michelle T. de Oliveira, Angélica N. Oliveira, Heloísa H.M. Soares, Cintia E. de P. Sabino, Adriano Silva, Luciana M. das Graças Carvalho, Maria Simões, Ricardo Gomes, Karina B. |
description | •Patients with breast cancer and doxorubicin-based chemotherapy present a hypercoagulable state.•Thrombin generation showed changes in patients using doxorubicin according to cardiotoxicity.•Thrombin generation parameters may be useful in monitoring hemostasis in these patients. |
doi_str_mv | 10.1016/j.thromres.2022.01.009 |
format | Article |
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subjects | Antineoplastic Combined Chemotherapy Protocols Breast cancer Breast Neoplasms - drug therapy Cardiotoxicity Cardiotoxicity - etiology Doxorubicin Doxorubicin - adverse effects Female Follow-Up Studies Hemostasis Hemostatics - therapeutic use Humans Thrombin generation |
title | Hemostatic status in women with breast cancer and cardiotoxicity associated to doxorubicin-based chemotherapy – A one-year follow-up study |
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