Array comparative genomic hybridisation results of non-syndromic children with the conotruncal heart anomaly

The study aimed to show the chromosomal copy number variations responsible for the aetiology in patients with isolated conotruncal heart anomaly by array comparative genomic hybridisation and identify candidate genes causing conotruncal heart disease. A total of 37 patients, 17 male, and 20 female,...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cardiology in the young 2022-02, Vol.32 (2), p.301-306
Hauptverfasser:	Mermer, Serdar, Şahin, Derya Aydın
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Anomalies Arrays Cardiac Anatomy and Pathology Cardiovascular diseases Child Child development Children Chromosomes Comparative Genomic Hybridization Complications Congenital diseases Copy number Coronary vessels DNA Copy Number Variations Etiology Female Genes Genetic disorders Genetic screening Genetic Testing Genomes Genomic analysis Genomics Heart Heart Defects, Congenital - genetics Heart diseases Humans Hybridization Male Original Article Patients Pediatrics Pulmonary arteries
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The study aimed to show the chromosomal copy number variations responsible for the aetiology in patients with isolated conotruncal heart anomaly by array comparative genomic hybridisation and identify candidate genes causing conotruncal heart disease. A total of 37 patients, 17 male, and 20 female, with isolated conotruncal heart anomalies, were included in the study. No findings indicated any syndrome in terms of dysmorphology in the patients.
ISSN:	1047-9511 1467-1107
DOI:	10.1017/S104795112100473X