The rs6942067 genotype is associated with a worse overall survival in young or non-smoking HPV-negative patients with positive nodal status in head and neck squamous cell carcinoma

•HNSCC patients with rs6942067 GG genotype have a worse overall survival.•HNSCC patients with rs6942067 GG genotype have higher occurrence of N+ tumors.•Occurrency of rs6940267 GG is higher for N+ patients young or without risk factors.•Patients with rs6942067 have higher risk of HNSCC than the gene...

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Veröffentlicht in:Oral oncology 2022-02, Vol.125, p.105696-105696, Article 105696
Hauptverfasser: Cardin, Guillaume B., Bernard, Monique, Bourbonnais, Jessica, Bahig, Houda, Nguyen-Tan, Phuc Félix, Filion, Edith, Soulieres, Denis, Gologan, Olguta, Ayad, Tareck, Guertin, Louis, Bissada, Eric, Rodier, Francis, Christopoulos, Apostolos
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container_title Oral oncology
container_volume 125
creator Cardin, Guillaume B.
Bernard, Monique
Bourbonnais, Jessica
Bahig, Houda
Nguyen-Tan, Phuc Félix
Filion, Edith
Soulieres, Denis
Gologan, Olguta
Ayad, Tareck
Guertin, Louis
Bissada, Eric
Rodier, Francis
Christopoulos, Apostolos
description •HNSCC patients with rs6942067 GG genotype have a worse overall survival.•HNSCC patients with rs6942067 GG genotype have higher occurrence of N+ tumors.•Occurrency of rs6940267 GG is higher for N+ patients young or without risk factors.•Patients with rs6942067 have higher risk of HNSCC than the general population.
doi_str_mv 10.1016/j.oraloncology.2021.105696
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subjects Genotype
Head and Neck Neoplasms - genetics
Humans
Oropharyngeal Neoplasms - pathology
Papillomavirus Infections - complications
Papillomavirus Infections - genetics
Squamous Cell Carcinoma of Head and Neck - genetics
title The rs6942067 genotype is associated with a worse overall survival in young or non-smoking HPV-negative patients with positive nodal status in head and neck squamous cell carcinoma
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