Action selection: Neuropeptidergic gates of behavior

Nervous systems continuously receive environmental signals with distinct behavioral meanings. To process ambiguous sensory inputs, neural circuits rely on hubs with compartmentalized synaptic structures. A new study has revealed how, in Drosophila larvae, this architecture with the local release of neuropeptides enables the control of flexible and context-dependent behavioral outcomes. Nervous systems continuously receive environmental signals with distinct behavioral meanings. To process ambiguous sensory inputs, neural circuits rely on hubs with compartmentalized synaptic structures. A new study has revealed how, in Drosophila larvae, this architecture with the local release of neuropeptides enables the control of flexible and context-dependent behavioral outcomes.