Protective Effect of Lactobacillus sporogenes against Arsenic-Induced Hematological Alterations in Male Albino Wistar Rats

The aim of the present study was to evaluate the arsenic-induced hemotoxicity and to evaluate the protective effects of Lactobacillus sporogenes in male albino Wistar rats. A total of 36 adult male albino Wistar rats were procured and divided into 3 groups of 12 animals each. Group 1 rats served as...

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Veröffentlicht in:	Biological trace element research 2022-11, Vol.200 (11), p.4744-4749
Hauptverfasser:	Bora, Swathi, Lakshman, M., Madhuri, D., Kalakumar, B., Udayakumar, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Albinism Arsenic Arsenite Biochemistry Biomedical and Life Sciences Biotechnology Blood Body weight Erythrocytes Evaluation Hematology Lactobacillus Leukocytosis Life Sciences Lymphopenia Males Malformations Monocytosis Morphology Neutrophilia Nutrition Oncology Parameters Reduction Rodents Scanning electron microscopy Sodium Sodium arsenite Spores Supplements Weekly
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Zusammenfassung:	The aim of the present study was to evaluate the arsenic-induced hemotoxicity and to evaluate the protective effects of Lactobacillus sporogenes in male albino Wistar rats. A total of 36 adult male albino Wistar rats were procured and divided into 3 groups of 12 animals each. Group 1 rats served as control, group 2 rats were administered sodium arsenite (@5 mg/kg BW/day), groups 3 rats were supplemented with L. sporogenes (@15 million spores/kg BW/day) along with sodium arsenite administered along with sodium arsenite orally daily for 28 consecutive days. Weekly body weights, hematological profile, and erythrocyte morphology were assessed. Significant ( P
ISSN:	0163-4984 1559-0720
DOI:	10.1007/s12011-021-03055-9