Hospital Outcomes Among Infants With Interrupted Aortic Arch With Simple and Complex Associated Heart Defects

Hospital Outcomes Among Infants With Interrupted Aortic Arch With Simple and Complex Associated Heart Defects

There is a lack of current, multi-institutional data regarding hospital outcomes of infants with interrupted aortic arch (IAA). We analyzed the Pediatric Health Information System database to identify infants with IAA who underwent repair during 2004 to 2019. We classified patients as simple or comp...

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Veröffentlicht in:The American journal of cardiology 2022-03, Vol.166, p.97-106
Hauptverfasser: Sanchez Mejia, Aura Andrea, Cambronero, Neil, Dongarwar, Deepa, Salihu, Hamisu Mohammed, Vigil-Mallette, Maria Anita, Garcia, Brisa Yran, Morris, Shaine Alaine
Format: Artikel
Sprache:eng
Schlagworte:
Aorta
Aorta, Thoracic - abnormalities
Aorta, Thoracic - surgery
Aortic arch
Aortic Coarctation - complications
Birth weight
Central nervous system
Child
Chromosome Deletion
Clustering
Codes
Complications
Confidence intervals
Congenital anomalies
Congenital defects
Congenital diseases
Defects
Demographics
DiGeorge Syndrome - complications
Ethnicity
Female
Gestational age
Heart Defects, Congenital
Heart surgery
Hospital costs
Hospitalization
Hospitals
Humans
Infant
Infants
Low birth weight
Male
Mortality
Patients
Pediatrics
Pulmonary arteries
Risk
Sepsis
Statistical analysis
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Beschreibung
Zusammenfassung:There is a lack of current, multi-institutional data regarding hospital outcomes of infants with interrupted aortic arch (IAA). We analyzed the Pediatric Health Information System database to identify infants with IAA who underwent repair during 2004 to 2019. We classified patients as simple or complex based on associated heart defects. We evaluated factors associated with hospital mortality and complications related to 22q11.2 deletion syndrome (22q11.2del) using mixed logistic regression, accounting for hospital clustering. In 1,283 infants included (904 simple, 379 complex), mortality was higher in the complex group (11.7% vs 4.4%, p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2021.11.032