Severe Polyarthralgia After Kidney Transplant

A 51-year-old woman had intense and worsening polyarthralgia and swelling of bilateral fingers and toes 1 year after kidney transplant complicated by Volvariella volvacea infection of the central nervous system. Her medications included tacrolimus, prednisolone, cinacalcet, and voriconazole. Alkalin...

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Veröffentlicht in:	JAMA : the journal of the American Medical Association 2022-01, Vol.327 (1), p.77-78
Hauptverfasser:	Allameen, Nur Azizah, Cho, Jiacai
Format:	Artikel
Sprache:	eng
Schlagworte:	Agaricales Alkaline phosphatase Alkaline Phosphatase - blood Antifungal Agents - adverse effects Arthralgia - chemically induced Arthralgia - diagnostic imaging Central nervous system Female Hand - diagnostic imaging Humans Kidney transplantation Kidney Transplantation - adverse effects Kidney transplants Kidneys Middle Aged Mycoses - drug therapy Mycoses - etiology Periostitis Prednisolone Radiography Tacrolimus Voriconazole Voriconazole - adverse effects
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Beschreibung
Zusammenfassung:	A 51-year-old woman had intense and worsening polyarthralgia and swelling of bilateral fingers and toes 1 year after kidney transplant complicated by Volvariella volvacea infection of the central nervous system. Her medications included tacrolimus, prednisolone, cinacalcet, and voriconazole. Alkaline phosphatase level was elevated, and radiography of the hands revealed periostitis. What is the diagnosis and what would you do next?
ISSN:	0098-7484 1538-3598
DOI:	10.1001/jama.2021.18866