Relationship between Antibody Levels and SARS-Cov-2 Reinfection

In this period when mutant strains are increasing all over the world, studies on how much humoral immunity will protect against the Severe Acute Respiratory Syndrome 2 (SARS-CoV-2) are quite limited. The aim of our study is to investigate the positivity and antibody levels of the COVID-19 reverse tr...

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Veröffentlicht in:Annals of clinical and laboratory science 2021-11, Vol.51 (6), p.750-755
Hauptverfasser: Islamoglu, Mehmet Sami, Cengiz, Mahir, Uysal, Betul Borku, Ikitimur, Hande, Ozdemir, Zeynep, Karamehmetoglu, Ahsen, Akbulut, Ayşe Ezgi, Bakdur, Ayşe Nur, Ozdemir, Azize, Kayıkcıoglu, Habibe, Ozdemir, Hatice, Uces, Rumeysa, Ersoy, Sema, Yavuzer, Serap
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Sprache:eng
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Zusammenfassung:In this period when mutant strains are increasing all over the world, studies on how much humoral immunity will protect against the Severe Acute Respiratory Syndrome 2 (SARS-CoV-2) are quite limited. The aim of our study is to investigate the positivity and antibody levels of the COVID-19 reverse transcription polymerase chain reaction (RT-PCR) test, the frequency of SARS-CoV-2 re-infection, and the protective antibody level against re-infection. Patients who were positive for COVID-19 IgG antibody between 1 July and 31 August were included in our study. The COVID-19 RT-PCR test positivity, age, gender and comorbidities of these patients were recorded before this date. The COVID-19 RT-PCR test positivity of these patients was followed from the National COVID-19 Database between September 1, 2020 and February 28, 2021. 1665 patients (female: male 683: 982, mean age 40.6±13.4 years). Among all patients, 14 patients had reinfection and the frequency of reinfection was 0.8%. It was observed that the frequency of reinfection was more frequent in patients with PCR negative (
ISSN:1550-8080