Serum iron concentrations in non-iron induced acute liver injury

Acute liver injury (ALI) is seen in conjunction with elevated iron concentrations in the setting of acute iron toxicity. However, occult or delayed presentations of iron toxicity can be difficult to identify clinically and there is limited data describing iron concentrations in ALI without a confirm...

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Veröffentlicht in:Clinica chimica acta 2022-01, Vol.525, p.12-14
Hauptverfasser: Mudan, Anita, Lebin, Jacob A., Wu, Alan H.B., Livshits, Zhanna
Format: Artikel
Sprache:eng
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Zusammenfassung:Acute liver injury (ALI) is seen in conjunction with elevated iron concentrations in the setting of acute iron toxicity. However, occult or delayed presentations of iron toxicity can be difficult to identify clinically and there is limited data describing iron concentrations in ALI without a confirmed history of iron overdose. This was a single center observational before-and-after study of adult patients who developed acute liver injury during hospitalization. Patients with a serum ALT > 500 U/L were identified by a daily hospital laboratory report and met inclusion if the ALT
ISSN:0009-8981
1873-3492
DOI:10.1016/j.cca.2021.12.008