Low ambient temperature as a novel risk factor of oral diseases: A time-series study

The seasonal variation of oral diseases has been observed in life, but the influences of oral diseases associated with non-optimal ambient temperature were unknown. To examine whether non-optimum ambient temperature is associated with increased risks of oral diseases. We conducted a time series study based on outpatient data from the Shanghai Health Information Center, containing all public hospitals in Shanghai from 2016 to 2019. Generalized additive models with distributed lagged nonlinear models were applied to fit the data. A total of 3,882,636 outpatient cases of oral diseases were collected. Low temperature (