Sex‐specific impact of major depressive disorder on 12‐year change in glycaemic status: Results from a nationwide cohort study of adults without diabetes in Germany

Aims There is evidence for an increased type 2 diabetes (T2D) risk associated with depression, but its role for diabetes prevention remains unclear. This study aimed to add insight by investigating the impact of major depressive disorder (MDD) on prospective glycaemic changes. Methods The study was...

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Veröffentlicht in:	Diabetic medicine 2022-03, Vol.39 (3), p.e14767-n/a
Hauptverfasser:	Nübel, Julia, Truthmann, Julia, Heidemann, Christin, Du, Yong, Paprott, Rebecca, Hapke, Ulfert, Kruse, Johannes, Scheidt‐Nave, Christa, Baumert, Jens
Format:	Artikel
Sprache:	eng
Schlagworte:	Antidiabetics Chronic illnesses Cohort analysis Demography Diabetes Diabetes mellitus (non-insulin dependent) Glucose glycaemic status change HbA1c Health care Hemoglobin longitudinal major depressive disorder Mental depression Mental health prediabetes Remission sex difference type 2 diabetes Womens health
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Zusammenfassung:	Aims There is evidence for an increased type 2 diabetes (T2D) risk associated with depression, but its role for diabetes prevention remains unclear. This study aimed to add insight by investigating the impact of major depressive disorder (MDD) on prospective glycaemic changes. Methods The study was based on a cohort of n = 1,766 adults without diabetes (776 men, 990 women; 18–65 years of age) who participated in the mental health supplement of the German National Health Interview and Examination Survey (GNHIES98‐MHS, 1997–1999) and in a follow‐up survey (DEGS1, 2008–2011). Glycaemic status was defined as normoglycaemia [HbA1c < 39 mmol/mol (
ISSN:	0742-3071 1464-5491
DOI:	10.1111/dme.14767