Sugammadex for reversal of neuromuscular blockade in pediatric patients: Results from a phase IV randomized study

Sugammadex for reversal of neuromuscular blockade in pediatric patients: Results from a phase IV randomized study

Background Few randomized studies have assessed recovery from rocuronium‐ or vecuronium‐induced moderate or deep neuromuscular blockade with sugammadex in pediatric participants. Aim To assess sugammadex for reversal of neuromuscular blockade in pediatric participants. Methods This was a randomized,...

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Veröffentlicht in:Pediatric anesthesia 2022-03, Vol.32 (3), p.436-445
Hauptverfasser: Voss, Tiffini, Wang, Aobo, DeAngelis, Matthew, Speek, Marcel, Saldien, Vera, Hammer, Gregory B., Wrishko, Rebecca, Herring, W. Joseph, Anderson, Brian
Format: Artikel
Sprache:eng
Schlagworte:
Anaphylaxis
Anaphylaxis - chemically induced
anesthesia
Anesthetics - adverse effects
Bradycardia - chemically induced
Cardiac arrhythmia
Child
Humans
Neostigmine
neuromuscular blockade
Neuromuscular Blockade - methods
Neuromuscular Nondepolarizing Agents - adverse effects
pediatric
Pediatrics
Rocuronium
Sugammadex
Sugammadex - adverse effects
Vecuronium Bromide - adverse effects
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Zusammenfassung:Background Few randomized studies have assessed recovery from rocuronium‐ or vecuronium‐induced moderate or deep neuromuscular blockade with sugammadex in pediatric participants. Aim To assess sugammadex for reversal of neuromuscular blockade in pediatric participants. Methods This was a randomized, phase IV, active comparator‐controlled, double‐blind study. Participants aged 2 to
ISSN:1155-5645
1460-9592
DOI:10.1111/pan.14370