The effect of manual pressure after subcutaneous injection on pain and comfort levels

•It is important to use evidence-based approaches in order to highlight the concept of quality in the delivery of nursing care. In our study, manual pressure application was used to reduce pain in patients receiving Enoxaparin Sodium treatment in SC injection and its effect was evaluated.•Manual pressure application has been found to significantly reduce SC injection pain. In this respect, it is thought that our research makes an important contribution to the literature.•An important contribution and originality of our study to the literature is to determine the comfort level of individuals who underwent SC injection. In the literature, there is no study evaluating the comfort level of an individual in SC injection. The pain experienced after subcutaneous injections can also disturb the comfort of the individual. An individual who experiences pain may refuse treatment by experiencing anxiety for subsequent injections. This experimental study was conducted to compare the effects of standard injection application and manual pressure application use on injection pain and comfort level of having an subcutaneous injection. This study was carried out on a single sample group with pre-post design. The individuals in the sample group constituted both the control and intervention groups of the study. In the sample group, subcutaneous injection was applied to the upper outer side of the right and left arms by the same nurse by applying standard application and manual pressure, and then the pain and comfort levels were determined using the VAS and Comfort Scale. It was determined that the mean pain scores of the SC injection application performed by applying manual pressure were statistically significantly lower than the SC injection application using the standard method. Again, it was determined that the mean comfort score of SC injection applied by applying manual pressure was statistically higher (p