A comparative study of olanzapine, aripiprazole and risperidone in the treatment of psychiatric and behavioral symptoms of Alzheimer's disease

To investigate the efficacy and safety of olanzapine, aripiprazole, and risperidone in the treatment of mental and behavioral symptoms of Alzheimer's Disease. A retrospective analysis was performed on the clinical data of 126 patients with Alzheimer's Disease from February 2018 to February...

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Veröffentlicht in:	Pakistan journal of pharmaceutical sciences 2021-09, Vol.34 (5(Special)), p.2053-2057
Hauptverfasser:	Zhu, Liang, Wu, Guanjin, Heng, Weiwei, Zang, Xuefeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alzheimer Disease - diagnosis Alzheimer Disease - drug therapy Alzheimer Disease - psychology Antipsychotic Agents - adverse effects Antipsychotic Agents - therapeutic use Aripiprazole - adverse effects Aripiprazole - therapeutic use Female Humans Male Olanzapine - adverse effects Olanzapine - therapeutic use Retrospective Studies Risperidone - adverse effects Risperidone - therapeutic use Time Factors Treatment Outcome
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Beschreibung
Zusammenfassung:	To investigate the efficacy and safety of olanzapine, aripiprazole, and risperidone in the treatment of mental and behavioral symptoms of Alzheimer's Disease. A retrospective analysis was performed on the clinical data of 126 patients with Alzheimer's Disease from February 2018 to February 2020. The patients were divided into group A (aripiprazole, n=44), group B (olanzapine, n=42) and group C (risperidone, n=40) based on the treatment method. Remarkably differences at different time points among the three groups were observed (P
ISSN:	1011-601X
DOI:	10.36721/PJPS.2021.34.5.SP.2053-2057.1