A Bright, Renal‐Clearable NIR‐II Brush Macromolecular Probe with Long Blood Circulation Time for Kidney Disease Bioimaging

Early detection of kidney disease is of vital importance due to its current prevalence worldwide. Fluorescence imaging, especially in the second near‐infrared window (NIR‐II) has been regarded as a promising technique for the early diagnosis of kidney disease due to the superior resolution and sensi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Angewandte Chemie International Edition 2022-01, Vol.61 (5), p.e202114273-n/a
Hauptverfasser:	Yao, Chenzhi, Chen, Ying, Zhao, Mengyao, Wang, Shangfeng, Wu, Bin, Yang, Yiwei, Yin, Dongrui, Yu, Peng, Zhang, Hongxin, Zhang, Fan
Format:	Artikel
Sprache:	eng
Schlagworte:	Addition polymerization Animals Bioimaging Blood circulation Boron Boron Compounds - chemistry Brightness Brushes Chemical compounds Diagnosis Fluorescence Fluorescent Dyes - chemistry Fluorophores Humans Infrared Rays Infrared windows Ischemia Kidney - diagnostic imaging Kidney cancer Kidney diseases Kidney Diseases - diagnostic imaging Kidneys Long blood circulation time Macromolecular probe Macromolecular Substances - chemistry Macromolecules Medical imaging Mice Molecular weight Near infrared radiation Optical Imaging Passive imaging Polymers Probes Renal function Renal-clearable Reperfusion Retention time Second near-infrared window Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Early detection of kidney disease is of vital importance due to its current prevalence worldwide. Fluorescence imaging, especially in the second near‐infrared window (NIR‐II) has been regarded as a promising technique for the early diagnosis of kidney disease due to the superior resolution and sensitivity. However, the reported NIR‐II organic renal‐clearable probes are hampered by their low brightness (ϵmaxΦf>1000 nm
ISSN:	1433-7851 1521-3773 1521-3773
DOI:	10.1002/anie.202114273