Imbalanced Folate and Vitamin B12 in the Third Trimester of Pregnancy and its Association with Birthweight and Child Growth up to 2 Years

Imbalanced Folate and Vitamin B12 in the Third Trimester of Pregnancy and its Association with Birthweight and Child Growth up to 2 Years

Scope Folic acid supplementation during pregnancy may lead to an imbalance when vitamin B12 intake is low (folate trap) and may affect child's growth. Methods The authors study the association between third trimester maternal intakes of folate and B12 and birthweight and postnatal growth of 263...

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Veröffentlicht in:Molecular nutrition & food research 2022-01, Vol.66 (2), p.e2100662-n/a
Hauptverfasser: Obeid, Rima, Eussen, Simone J.P.M., Mommers, Monique, Smits, Luc, Thijs, Carel
Format: Artikel
Sprache:eng
Schlagworte:
Biomarkers
Birth Weight
birthweight
child growth
Cohort Studies
Cyanocobalamin
Diet
Dietary intake
Erythrocytes
Female
folate trap
Folic acid
Folic Acid - administration & dosage
Folic Acid - metabolism
Homocysteine
Humans
imbalanced folate and vitamin B12
Infant
Infant, Newborn
Infants
Pregnancy
Pregnancy Trimester, Third
Vitamin B
Vitamin B 12 - administration & dosage
Vitamin B 12 - metabolism
Vitamin B12
Vitamins
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Zusammenfassung:Scope Folic acid supplementation during pregnancy may lead to an imbalance when vitamin B12 intake is low (folate trap) and may affect child's growth. Methods The authors study the association between third trimester maternal intakes of folate and B12 and birthweight and postnatal growth of 2632 infants from the KOALA Birth Cohort Study. Plasma vitamin biomarkers are measured in 1219 women. Results Imbalanced total intakes (folate > 430 µg day−1 combined with B12  745 nmol L−1 and plasma B12
ISSN:1613-4125
1613-4133
DOI:10.1002/mnfr.202100662