Etilefrine infusion for idiopathic chyle leakage in a critically ill child

An examination in our emergency department showed signs of respiratory distress and hypoxemia, and the patient was admitted to the pediatric intensive care unit for respiratory failure. Table 1 Clinical course and chyle output Hospital day Octreotide (μg/kg/h) Etilefrine (μg/kg/h) Intake Drainage tube output (mL/kg/day) Event 5 NPO Intubation 6 TPN 138.8 7 0.5 119.6 8 1 111.4 9 2 164.5 10 4 103.1 11 10 50.6 13 15 28.3 Extubation 15 20 14.3 Chest drainage, tube removal 23 MCT 1.7 mL/kg/day 2.3 24 MCT 5.2 mL/kg/day 0.3 25 MCT 8.7 mL/kg/day 3.4 26 MCT 10.7 mL/kg/day 3.1 27 MCT 15.7 mL/kg/day 5.5 28 0.5 TNP 3.6 29 1 5.2 30 1.7 34 0 37 MCT 2.3 ml/kg/day 0 38→48 MCT 6.4→98 ml/kg/day 0 Abdominal drainage, tube removal (day 42) 49→53 20→0 (tapered by 25% per day) MCT 98 ml/kg/day 56→60 0 1.0→0 (tapered by 40% per day) MCT, medium chain triglyceride; NPO, nil per os; TPN, total parenteral nutrition. [...]our findings suggested that etilefrine may be a novel, viable option in the conservative management of chyle leakage, although the etilefrine dosages appropriate for pediatric use have yet to be established.